I have a sako 75 6.5x47, throated for 140 grain bullets and friend has a sako 75 6.5 creedmoor with similar throat. Shooting our to 1000y, he has 2 moa less elevation but otherwise nothing in it, wind calls make more of a difference.
I am having a 6.5 creedmoor built so can use factory ammo if need be, just something else to think about. Sometimes I just don’t get time to reload.